The protein encoded by this gene is part of a complex termed negative elongation factor ( NELF ) which represses RNA polymerase II transcript elongation.
2.
This protein has also been shown to be a member of the NELF ( negative elongation factor ) protein complex that participates in the regulation of RNA polymerase II transcription elongation.
3.
NELF-B is a subunit of negative elongation factor ( NELF ), which also includes NELF-A ( WHSC2; MIM 606026 ), either NELF-C or NELF-D ( TH1L; MIM 605297 ), and NELF-E ( RDBP; MIM 154040 ).
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